Apyramidra Yxunni & Oybmyltd Equation Card (嗜酸细胞增生性淋巴肉芽腫)

$1,200.00

Apyramidra Yxunni & Oybmyltd Equation Card

嗜酸细胞增生性淋巴肉芽腫是主要發生在面頸部,特別是腮腺區的良性肉芽腫樣病變。本病又稱為嗜酸細胞增生性淋巴肉芽腫。
病因不明,近年來研究認為是一種與白色念珠菌有關的免疫性疾病。本病多見於青年或中年男性,也可發生於女性。肉芽腫腫塊的大小不一,柔韌,無包膜,切面呈灰白色,雜以白色、黃色和灰色區,在腮腺區可見病變與腮體堅貼,或侵入腺體實質小葉之間,但不累及面神經,肉芽腫周圍的淋巴結可腫大。鏡下見腫塊呈肉芽腫狀,有大量淋巴細胞和嗜酸粒細胞浸潤,出現淋巴濾泡,且常為增生型,嗜酸細胞浸潤呈瀰漫性,尚可見到中等量的漿細胞,以及不等量結締組織和膠原纖維,病變區皮膚、皮下組織及腺體內亦可見到上述的病理改變。腫塊周圍淋巴可見淋巴細胞增生及瀰漫性嗜酸細胞浸潤。表現為腮腺區軟組織無痛性腫塊,緩慢增大,平均病期可長達7-8年,伴有輕微發熱和倦怠感。病變亦可發生在眼眶周圍、顴頰部、頜下和頦下以及上臂、股部等軟組織中,不侵犯骨質,可為單發腫塊,也有多發。腫塊初呈軟、橡皮樣,日久後可變為硬韌狀,界限不清,無壓痛,表面皮膚增厚、粗糙、瘙癢、色素沉著呈灰褐色,並與腫塊緊密相連,但腫塊基底可以推動,有的可時大時小,偶見有自行緩解。區域性淋巴結或全身表淺淋巴結可腫大,約1-3cm大小,不痛,無壓痛,也不化膿。

It is a benign granulomatous lesion that mainly occurs in the face and neck, especially in the parotid area. This disease is also called eosinophilic lymphogranuloma.
The cause of the disease is unknown. In recent years, studies have considered it to be an immune disease related to Candida albicans. This disease is more common in young or middle-aged men, but can also occur in women. Granuloma masses vary in size, are flexible and have no capsule. The cut surface is off-white, mixed with white, yellow, and gray areas. In the parotid area, the lesions can be seen to adhere to the parotid body, or invade between the parenchymal lobules of the gland, but it does not involve Facial nerve, lymph nodes around granuloma can be enlarged. Under the microscope, the mass was seen as granulomatous, with a large number of lymphocytes and eosinophils infiltrating, and lymphoid follicles appeared, and they were often proliferative. The same amount of connective tissue and collagen fibers, the above-mentioned pathological changes can also be seen in the skin, subcutaneous tissue and glands of the diseased area. Lymphatic proliferation and diffuse eosinophilic infiltration can be seen in the lymph around the mass. It manifests as a painless mass in the soft tissue of the parotid gland area, slowly increasing, and the average duration of illness can be as long as 7-8 years, accompanied by mild fever and fatigue. Lesions can also occur in soft tissues around the orbit, zygomatic cheeks, submandibular and submental, upper arms, thighs and other soft tissues. They do not invade bone. They can be single or multiple. The lump is soft and rubber-like at first, and becomes hard and tough after a long time, with unclear boundaries and no tenderness. The surface skin is thickened, rough, itchy, and the pigmentation is gray-brown, and it is closely connected to the lump, but the base of the lump can be Push, sometimes it can be big or small, and occasionally it can relieve itself. Regional lymph nodes or superficial lymph nodes all over the body can be enlarged, about 1-3 cm in size, not painful, not tender, nor suppurative.